The objective of this study was to validate recommended reprocessing methods for Ipas manual vacuum aspiration (MVA) devices. The study found that Ipas MVA devices were not negatively affected following validated instrument reprocessing methods for high-level disinfection (HLD) or sterilization for up to 25 reuse cycles. STERRAD and Cidex OPA did not meet assessed standards and are therefore not recommended. Strict adherence to guidance is critical for effective reprocessing of instruments.